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FERID MURAD
BS, MD, PhD
Picture
  • Western Reserve University, DePauw University, Case Western
  • Taught pharmacology at the University of Virginia School of Medicine, Charlottesville (1975-81), Stanford (1981-89), Northwestern University (1988), medical school in University of Texas, House (1977)
  • Ventured into private sector as a vice president of Abbott Laboratories (1988-92)
  • President of Molecular Geriatrics Corporation (1993-95)​
  • Awarded 1998 Nobel Prize in Physiology or Medicine for the discovery that nitric oxide (NO) acts as a signaling molecule in the cardiovascular system
Ferid Murad, (born Sept. 14, 1936, Whiting, Ind., U.S.), American pharmacologist, who, along with Robert F. Furchgott and Louis J. Ignarro ,was co-awarded the 1998 Nobel Prize in Physiology or Medicine for the discovery that nitric oxide (NO) acts as a signaling molecule in the cardiovascular system. Their combined work uncovered an entirely new mechanism for how blood vessels in the body relax and widen. 

Murad received his M.D. and Ph.D. from Western Reserve University (later Case Western Reserve University) in Cleveland, Ohio, in 1965. In addition to his clinical practice, Murad taught pharmacology at the University of Virginia School of Medicine, Charlottesville (1975–81), at Stanford University (1981–89), and then at Northwestern University (1988). While at Stanford he ventured into the private sector as a vice president of Abbott Laboratories (1988–92) and then became president of the Molecular Geriatrics Corporation (1993–95). He began teaching at the medical school of the University of Texas, Houston, in 1997.
​

In 1977 Murad showed that nitroglycerin and several related heart drugs induce the formation of nitric oxide and that the colourless, odorless gas acts to increase the diameter of blood vessels in the body. Furchgott and Ignarro built on this work. About 1980 Furchgott demonstrated that cells in the endothelium, or inner lining, of blood vessels produce an unknown signaling molecule, which he named endothelium-derived relaxing factor (EDRF). This molecule signals smooth muscle cells in blood vessel walls to relax, dilating the vessels. Ignarro’s research, conducted in 1986 and done independently of Furchgott’s work, identified EDRF as nitric oxide. These discoveries led to the development of the anti-impotence drug  sildenafil citrate (Viagra) and had the potential to unlock new approaches for understanding and treating other diseases.
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  • Home
  • Team
    • TEAM HISTORY >
      • Ted Driscoll
      • Michele Colucci
      • Eric Weiss
      • David Kirk
      • Maureen Downey
      • Arthur Henderson
      • Gianna Conci Orozco
      • L Jasmine Kim
      • Robert Weigle
      • Laura Yecies
      • Steve Goldenberg
      • Vivian Lu
    • Fellows >
      • Ethan Gauvin
      • Caroline Gezon
      • Ananya Sheth
      • Michelle Volz
      • Adam Aguilera
      • Joanna Zhu
      • Andy Chen
      • Andrew Hicks
      • Shreya Dwarakanath
      • Sam Lambert
      • Charlton Hook
      • Sylvia Bouloutas
      • Alexandra Davis
      • Alexander Behrens
      • Melania Antoszko
      • Michael Solotke
      • Arpan Soparkar
      • Changhao Wei
      • Irene Manousiouthakis
      • Vivek Maheshwari
      • Isha Godara
      • Eddie Chan
      • Joseph Kemp
      • Michael Tellini
      • Dariush Sarrafzadeh
      • Dev Sharma
      • Alan Quigley
      • Tristan Zhang
      • Austin Hwang
      • Ivan Fang
      • Leyton Ho
      • Saumya Choudhary
      • Srinidhi Sankar
      • Yashaswi Kumar
      • Yifu Wu
      • Ajay Sharma
      • Amber Bowie
      • Anthony Obi Jr
      • Bob Chien
      • Brandon Toushan
      • Carter Burleson
      • Chia-Fen Hsieh
      • Elitsa Papazova
      • Emily Stotland
      • Eric Li
      • Kristina Schlegel
      • Minshan Chen
      • Nitin Naik
      • Teryn Isabel Mitchell
      • Varunram Ganesh
      • YiChiang Chan
      • Yvette Lu
      • Anran Li
      • Sneha Kasuganti
  • ADVISORS
    • Russ Altman
    • Saul A. Fox
    • Deborah DiSanzo
    • Dr. Carlos D. Bustamante
    • Carl Wieman
    • Girish Narayan
    • Ferid Murad
  • Impact
    • Chantal Miklosi
    • Malekeh Amini
    • Melanie Mahtani
    • Marie-Claude Marchand
    • Minnie Sarwal
    • Claudia Chevrefils
    • Lucy Lu
  • FOCUS
  • Portfolio Companies